Cancer - Allinky Biopharma

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AIK4 is a novel cluster of chemical compounds (small molecules) discovered by Allinky that selectively bind to Ras at a set of novel allosteric sites. These compounds have been seen to be effective in tumor cell lines and in animal efficacy studies (xenografts). These compounds are aimed to treat Ras mutation or overexpression-bearing tumors such as those found in non-Hodgkin lymphomas (NHLs) and specifyc types of lung, colorectal and pancreatic cancer, with special attention to cancer with a low or null response rate to VEGF-antibody treatment.

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